Hubungan Tingkat Pengetahuan Ibu Hamil tentang Hepatitis B dengan Kepatuhan Skrining HBsAg pada Pelayanan Antenatal Care di UPT Puskesmas Sekotong Kabupaten Lombok Barat

Khairul Umam; Lalu Khairil  Anwar

doi:10.71094/jonp.v2i1.381

Authors

Khairul Umam Sekolah Tinggi Ilmu Kesehatan (STIKES) Mataram, Mataram, Indonesia Author
Lalu Khairil Anwar Sekolah Tinggi Ilmu Kesehatan (STIKES) Mataram, Mataram, Indonesia Author

DOI:

https://doi.org/10.71094/jonp.v2i1.381

Keywords:

Hepatitis B, Pregnant Women, Knowledge, HBsAg Screening, Antenatal Care

Abstract

Hepatitis B remains a major global health concern, particularly among pregnant women because of the risk of transmission from mother to child. Early detection through Hepatitis B surface antigen (HBsAg) screening during antenatal care is considered an important preventive measure to reduce the possibility of vertical transmission and its long-term consequences for infants. However, the level of knowledge among pregnant women may influence their willingness to undergo the recommended screening. This study aimed to examine the relationship between pregnant women's knowledge about hepatitis B and their compliance with HBsAg screening during antenatal care services at UPT Puskesmas Sekotong, West Lombok Regency. A quantitative analytic study with a cross-sectional approach was conducted involving pregnant women who attended antenatal care services at the health center. Data on respondents’ knowledge regarding hepatitis B were collected using a structured questionnaire, while compliance with HBsAg screening was obtained from maternal health records. The collected data were analyzed using descriptive statistics and the chi-square test to determine the association between the variables. The findings indicated that most respondents had moderate to good knowledge regarding hepatitis B infection and its prevention. A majority of pregnant women had undergone HBsAg screening during antenatal visits. Statistical analysis showed a significant relationship between the level of knowledge of pregnant women and their compliance with HBsAg screening (p < 0.05). Pregnant women who possessed better knowledge were more likely to participate in the screening process. These findings highlight the importance of strengthening health education during antenatal care to increase maternal awareness and encourage early detection of hepatitis B infection in pregnancy.

References

Adeyemi, A. B., Enabor, O. O., Ugwu, I. A., Bello, F. A., & Olayemi, O. O. (2013). Knowledge of hepatitis B virus infection, access to screening and vaccination among pregnant women in Ibadan, Nigeria. Journal of Obstetrics and Gynaecology, 33(2), 155–159. https://doi.org/10.3109/01443615.2012.711389

Brown, R. S., McMahon, B. J., Lok, A. S., Wong, J. B., Ahmed, A. T., Mouchli, M. A., Wang, Z., Prokop, L. J., Murad, M. H., & Mohammed, K. (2016). Antiviral therapy in chronic hepatitis B viral infection during pregnancy. Hepatology, 63(1), 319–333. https://doi.org/10.1002/hep.28302

Chotun, N., Preiser, W., van Rensburg, C., Fernandez, P., Theron, G., Glebe, D., & Andersson, M. (2017). Point-of-care screening for hepatitis B virus infection in pregnant women attending antenatal clinics. PLOS ONE, 12(7), e0181267. https://doi.org/10.1371/journal.pone.0181267

Gebrecherkos, T., Girmay, G., Lemma, M., & Negash, M. (2020). Knowledge, attitude, and practice towards hepatitis B virus among pregnant women attending antenatal care. International Journal of Hepatology, 2020, 5617603. https://doi.org/10.1155/2020/5617603

Hyun, M. H., Lee, Y. S., Kim, J. H., Je, J., & Kim, L. H. (2017). Systematic review with meta-analysis: The efficacy and safety of tenofovir to prevent mother-to-child transmission of hepatitis B virus. Alimentary Pharmacology & Therapeutics, 45(12), 1493–1505. https://doi.org/10.1111/apt.14079

Kwon, S. Y., & Lee, C. H. (2011). Epidemiology and prevention of hepatitis B virus infection. Korean Journal of Hepatology, 17(2), 87–95. https://doi.org/10.3350/kjhep.2011.17.2.87

Liang, T. J. (2009). Hepatitis B: The virus and disease. Hepatology, 49(S5), S13–S21. https://doi.org/10.1002/hep.22881

Loarec, A., Nguyen, A., Molfino, L., Chissano, M., Madeira, N., Rusch, B., Staderini, N., Couto, A., Ciglenecki, I., & Antabak, N. (2021). Prevention of mother-to-child transmission of hepatitis B virus in antenatal care and maternity services in Mozambique. Bulletin of the World Health Organization, 100(1), 60–69. https://doi.org/10.2471/BLT.20.281311

Munivenkatappa, S., & Govindaraj, S. M. (2019). A study evaluating knowledge and attitude towards hepatitis B among pregnant women. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 8(8), 3183–3188. https://doi.org/10.18203/2320-1770.ijrcog20193532

Nnaji, A. O., & Nnaji, R. N. I. (2023). Knowledge and practice of hepatitis B screening services among pregnant women in Enugu South Local Government Area. British Journal of Multidisciplinary and Advanced Studies, 4(3), 14–27. https://doi.org/10.37745/bjmas.2022.0189

Odagami, M., Iwata, A., Kubota, K., Kurasawa, K., Okuda, M., Hirabuki, T., Saji, H., & Hasegawa, T. (2023). Awareness of infectious disease screening during early pregnancy and knowledge about vertical transmission. Maternal and Child Health Journal, 27(5), 933–943. https://doi.org/10.1007/s10995-023-03597-5

Op de Coul, E. L. M., Hahné, S., van Weert, Y., Oomen, P., Smit, C., van der Ploeg, K., Notermans, D., Boer, K., & van der Sande, M. (2011). Antenatal screening for HIV, hepatitis B and syphilis in the Netherlands. BMC Infectious Diseases, 11, 185. https://doi.org/10.1186/1471-2334-11-185

Pan, C. Q., & Zhang, J. X. (2005). Natural history and clinical consequences of hepatitis B virus infection. International Journal of Medical Sciences, 2(1), 36–40. https://doi.org/10.7150/ijms.2.36

Schillie, S., Murphy, T. V., Sawyer, M., Ly, K., Hughes, E., Jiles, R., & Reilly, M. (2018). CDC recommendations for hepatitis B screening during pregnancy. MMWR Recommendations and Reports, 67(1), 1–31. https://doi.org/10.15585/mmwr.rr6701a1

Terrault, N. A., Bzowej, N. H., Chang, K. M., Hwang, J. P., Jonas, M. M., & Murad, M. H. (2018). AASLD guidelines for treatment of chronic hepatitis B. Hepatology, 67(4), 1560–1599. https://doi.org/10.1002/hep.29800

World Health Organization. (2017). Global hepatitis report 2017. https://doi.org/10.1016/S0140-6736(16)30571-0

World Health Organization. (2022). Hepatitis B. https://doi.org/10.1016/S0140-6736(22)00299-2

Yao, N., Fu, S., Wu, Y., Tian, Z., Feng, Y., Li, J., Luo, X., Yang, Y., Ji, F., Chen, Y., & Zhao, Y. (2022). Incidence of mother-to-child transmission of hepatitis B in relation to maternal antiviral prophylaxis. Acta Obstetricia et Gynecologica Scandinavica, 101(11), 1197–1206. https://doi.org/10.1111/aogs.14448

Lubis, R., Novelia, S., & Nufus, H. (2022). Characteristics of pregnant women with reactive HBsAg. Health Technology Journal, 1(2), 45–52. https://doi.org/10.53713/htechj.v1i2.33

Kahar, F. (2025). Relationship between knowledge and behavior of pregnant women with triple elimination screening. Jaringan Laboratorium Medis, 7(2), 86–97. https://doi.org/10.31983/jlm.v7i2.12971

Ainunnissa, N., Setyowati, D., & Prasetyo, B. (2023). Pregnant women’s knowledge regarding hepatitis B prevention efforts in newborns. International Journal of Health Science, 4(1), 44–52. https://doi.org/10.55606/ijhs.v4i1.3471

Maryam, S., & Handayani, E. T. (2025). Analysis of pregnant women’s knowledge about hepatitis B regarding laboratory examinations. Journal for Quality in Women’s Health, 8(1), 5–11. https://doi.org/10.30994/jqwh.v8i1.282

Sabeena, S., & Ravishankar, N. (2022). Horizontal modes of transmission of hepatitis B virus: A systematic review and meta-analysis. Iranian Journal of Public Health, 51(10), 2181–2193. https://doi.org/10.18502/ijph.v51i10.10977

Okeke, E., et al. (2023). Perceived risk factors and preventive practices of hepatitis B viral infection among pregnant women. Sexual & Reproductive Healthcare, 37, 100896. https://doi.org/10.1016/j.srhc.2023.100896